Let's first start with using crayons. It's usually one of the first coloring material introduced to little children because it's perfect for kids to use since there's jumbo sized ones that they can easily handle without breaking it in half. It's also a great material for bigger kids and even grown_ups because it has a wide range of colors to choose from.
Overlap Colors to Create a Blended Look. I like to lightly color the dominate color first and leave a bit of paper exposed for the wax of the second color to cling to. In the liver I colored (below), I started by coloring a layer of red, then I colored some brown on top. Then I colored more red over the top. I find this kind of layering to be really fun!