Use good quality crayons (Crayola works well) for the best results. Making the fill color darker around the edges is a good technique for adding dimension. As you work, don't press too hard. It's better to add layers of color than to have too much color that you can't remove. Take care to color evenly and without causing color streaks. When you're finished, place a piece of scrap fabric over the coloring and iron the paper on a high setting. This will heat set the coloring and remove excess wax.
A Variety of Pressure Creates Emphasis. If there are some areas you want to accent, you can press a little harder on the crayon and end up with a darker, more intense color. This is another good reason to color lightly for full coverage. For example, in this picture of the heart below, I pressed harder when tracing the lines within the heart and in the vein and artery openings. I did the same thing when coloring the muscles and the brain.