I think the biggest problem people have when drawing with crayons is that they regress to being five years old again. They hold the crayon like they're coloring again, instead of applying it like a fine art medium. Another problem is that many people want to make it perform like colored pencils. While similar in application, they are quite different. You should not use crayons and expect them to behave like colored pencils. You'll be setting yourself up for disappointment.
Color Outside the Lines Sometimes. In some circumstances, like this one, you can color outside the lines because you'll cut the piece out afterwards. This allows you to use large consistent strokes, as you can see in the red kidney above and on the right. This is an especially helpful tip for younger students who are coloring the organs in this My Body project. (Just be sure not to use this tactic on the upper half of the heart in the My Body book because we won't trim around all those veins and arteries.)