Color Outside the Lines Sometimes. In some circumstances, like this one, you can color outside the lines because you'll cut the piece out afterwards. This allows you to use large consistent strokes, as you can see in the red kidney above and on the right. This is an especially helpful tip for younger students who are coloring the organs in this My Body project. (Just be sure not to use this tactic on the upper half of the heart in the My Body book because we won't trim around all those veins and arteries.)
Many crayon artists (you can find a few online) use solvents to soften their appearance. It can be a wonderful look but, personally, I love the pixilated look the crayon creates when applied just as is. Look at the art examples in this post _ you can see the speckled look crayon has when applied in layers. This adds to the realism, especially when creating an out_of_focus background, such as in these two images.