Stay sharp! Good quality pencils will allow the lead to be sharpened regularly. Needle sharp tips on your pencils are perfect for applying detail and getting the precision required to color intricate areas of a design. Thinner points will give you more control over the color produced, big fat rounded ends on your pencils make it difficult to get the brightest colors.
If you have a corner or turn that makes it really awkward not to change direction, you can either color using curved lines or color using very small circles instead of lines. Just keep in mind that how you color will always be visible and will create the appearance of texture.