Always Color in a Consistent Direction. This is my first tip. It will make a bigger impact on the end result than anything else and any age can use it! The changes in direction, shown on the red kidney below, on the left side, are what make it look sloppy, even though I carefully stayed in the lines. Coloring in a consistent direction, as seen on the other kidney, is easier on the eyes and ends up looking very tidy!
Build your colors gradually, and layer them. Apply a light undertone, and build darker colors slowly on top. Crayons can actually be more difficult to layer with due to the high wax content. Don't confuse them with colored pencils! If you want the "look" colored pencil, just use that instead.