Some colors are more transparent than others. Some colors are very opaque. Test your colors on a separate piece of paper to see how they work together. Too many layers of crayon can make the colors resist each other. This can make it harder to add more color. Use as few colors as possible to get your end result.
Color Outside the Lines Sometimes. In some circumstances, like this one, you can color outside the lines because you'll cut the piece out afterwards. This allows you to use large consistent strokes, as you can see in the red kidney above and on the right. This is an especially helpful tip for younger students who are coloring the organs in this My Body project. (Just be sure not to use this tactic on the upper half of the heart in the My Body book because we won't trim around all those veins and arteries.)