If you want a clean and bold look for your picture, you can use colored markers for the color. It has a wide variety of colors and you can choose between fine tipped ones and broad tips depending on your needs. There are also refillable markers where you can just purchase ink whenever it dries up or loses its color. It's also an easy material to use. You just have to apply a single coat on the drawing. You can also add some more details using either a white colored pencil or a white inked pen.
Many crayon artists (you can find a few online) use solvents to soften their appearance. It can be a wonderful look but, personally, I love the pixilated look the crayon creates when applied just as is. Look at the art examples in this post _ you can see the speckled look crayon has when applied in layers. This adds to the realism, especially when creating an out_of_focus background, such as in these two images.