If you want a clean and bold look for your picture, you can use colored markers for the color. It has a wide variety of colors and you can choose between fine tipped ones and broad tips depending on your needs. There are also refillable markers where you can just purchase ink whenever it dries up or loses its color. It's also an easy material to use. You just have to apply a single coat on the drawing. You can also add some more details using either a white colored pencil or a white inked pen.
A Variety of Pressure Creates Emphasis. If there are some areas you want to accent, you can press a little harder on the crayon and end up with a darker, more intense color. This is another good reason to color lightly for full coverage. For example, in this picture of the heart below, I pressed harder when tracing the lines within the heart and in the vein and artery openings. I did the same thing when coloring the muscles and the brain.